Inflammatory Content
Inflammatory Content is a podcast about immunology and biomedical sciences more broadly. UC San Diego immunologist Dr. Kellen Cavagnero PhD reviews the latest high-impact original articles and discusses all things science with leading researchers in the field. Inflammatory Content has been featured in Nature and received sponsorship from the NIH.
Sat, March 08, 2025
#25: Immuno-endocrinology with Dr. Dequina Nicholas, Ph.D.
In this episode, Dr. Kellen Cavagnero is joined by Dr. Dequina Nicholas. Dr. Nicholas is an Assistant Professor at the University of California Irvine in the Department of Molecular Biology and Biochemistry. Her laboratory studies endocrine diseases, including type 2 diabetes and polycystic ovary syndrome. Specifically, her group investigates the intersection of the nutrient environment, the immune system, and metabolic disease using a combination of molecular and cellular biology, transgenic mouse models, cytokine profiling, and flow cytometry. Dr. Nicholas is the recipient of numerous awards including the NIH Director’s New Innovator Award. In their conversation, Kellen and Dequina discuss type 2 diabetes, polycystic ovary syndrome, lipid antigen presentation, transitioning to independence, DEI, and more. Relevant Links: • Nicholas Lab Website: https://nicholaslab.bio.uci.edu/ • Transitioning to Independence: https://pubmed.ncbi.nlm.nih.gov/35644775/ • TikTok: @NicholasLab • X: @QuinaScience • Bluesky: @quinascience.bsky.social If you enjoy Inflammatory Content and want to help me keep the conversations going, consider supporting the podcast! You can write a review, share this episode with friends and colleagues, or make a donation to help keep the show ad-free and thriving. Your contributions, big or small, go directly toward covering production costs and allow me to bring you even more Inflammatory Content. You can donate directly here: https://venmo.com/Kellen-Cavagnero. I’d love to hear from you! Feel free to reach out with questions, feedback, or topic suggestions via email at kcavagnero@gmail.com, on X @KellenCavagnero, or connect with me on LinkedIn. Stay curious and keep exploring at www.inflammatorycontent.com.
Thu, January 16, 2025
#24: AI Generated Podcast on Immune-Acting Fibroblasts
Today we’re going to do a journal club, but it will not be your run of the mill journal club. Everyone who knows me knows I am always searching for the latest technology that can increase my efficiency. Lately, I have been especially attuned to the newest developments in artificial intelligence.Well, I recently discovered a new AI tool by Google called NotebookLM that creates audio overviews of documents. What this means is that it will--within minutes--create a journal club podcast if you upload a research article. It is BANANAS! There are a few minor instances where the speech is buggy and words are mis-pronounced, but, overall, I am super impressed with how well it communicates research findings—very accessible and high fidelity. So today I bring to you an experimental AI generated journal club on my 2 latest research articles. The first article was published in the Journal of Experimental Medicine in early 2024 and the second was published as a preprint (meaning not yet peer reviewed) on bioRxiv in late 2024. Relevant Links: • Paper 1: https://pubmed.ncbi.nlm.nih.gov/38393304/ • Paper 2: https://pubmed.ncbi.nlm.nih.gov/38979312/ If you enjoy Inflammatory Content and want to help me keep the conversations going, consider supporting the podcast. You can write a review, share this episode with friends and colleagues, or make a donation to help keep the show ad-free and thriving. Your contributions, big or small, go directly toward covering production costs and allow me to bring you even more Inflammatory Content. You can donate directly here: https://venmo.com/Kellen-Cavagnero I’d love to hear from you. Feel free to reach out with questions, feedback, or topic suggestions via email at kcavagnero@gmail.com, on X (formerly Twitter) @KellenCavagnero, or connect with me on LinkedIn.
Sat, November 30, 2024
#23: The PhD Fellowship Application Survival Guide
One of the most common questions I get from undergraduate and graduate students is: How do I get a Ph.D. fellowship? During my Ph.D., I was fortunate to be awarded two fellowships, and I’ve received two more as a postdoc. In this solo episode, I provide an overview of the who, what, where, when, why, and how of Ph.D. fellowship applications, with the goal of helping you secure a fellowship to support your research. Please reach out to me if you would like the PowerPoint version of The Ph.D. Fellowship Application Survival Guide. Relevant Links: • NOFO Database: https://research.jhu.edu/rdt/funding-opportunities/graduate/ • NIH Grant Writing Course: https://bouviergrant.com/ If you enjoy Inflammatory Content and want to help me keep the conversations going, consider supporting the podcast. You can write a review, share this episode with friends and colleagues, or make a donation to help keep the show ad-free and thriving. Your contributions, big or small, go directly toward covering production costs and allow me to bring you even more Inflammatory Content. You can donate directly here: https://venmo.com/Kellen-Cavagnero. I’d love to hear from you. Feel free to reach out with questions, feedback, or topic suggestions via email at kcavagnero@gmail.com, on X (formerly Twitter) @KellenCavagnero, or connect with me on LinkedIn. Stay curious and keep exploring at www.inflammatorycontent.com.
Sat, October 26, 2024
#22: Mpox (formerly monkeypox) with Dr. Aaron Oom, Ph.D.
In this episode, Kellen is joined by Dr. Aaron Oom, a Postdoctoral Scholar in the lab of Dr. Mark Mulligan at NYU Langone Health. Aaron is an expert in virology and immunology. He completed his Ph.D. in the lab of Dr. John Guatelli’s at UC San Diego. Aaron has made significant contributions to our understanding of viruses including HIV, Zika, and Dengue. Now, as a Postdoctoral Scholar in the Mulligan lab, he’s focused on Mpox (formerly known as monkeypox), which has recently re-emerged as a major global health threat. In this conversation, Kellen and Aaron discuss Aaron’s recent mpox publication, the challenges of transitioning to independence, the tough decisions around “killing” projects that aren’t working, and much more. Relevant Links: • Mulligan Lab Website: https://med.nyu.edu/research/mulligan-lab/ • Aaron’s MedRxiv preprint: https://www.medrxiv.org/content/10.1101/2024.01.28.24301893v1 • Mpox review: https://www.nature.com/articles/s41577-022-00775-4 If you enjoy Inflammatory Content and want to help me keep the conversations going, consider supporting the podcast! You can write a review, share this episode with friends and colleagues, or make a donation to help keep the show ad-free and thriving. Your contributions, big or small, go directly toward covering production costs and allow me to bring you even more Inflammatory Content. You can donate directly here: https://venmo.com/Kellen-Cavagnero. I’d love to hear from you! Feel free to reach out with questions, feedback, or topic suggestions via email at kcavagnero@gmail.com, on X (formerly Twitter) @KellenCavagnero, or connect with me on LinkedIn. Stay curious and keep exploring at www.inflammatorycontent.com.
Mon, August 26, 2024
#21: Functional genomics identifies a novel therapeutic target for inflammatory bowel disease
Genome-wide association studies (GWAS) have identified thousands of disease-associated genetic variants. Many of these variants lie in non-coding regions of the genome, making interpretation of GWAS difficult and leading to poor translation into therapeutics. In this episode, Kellen reviews an exciting original article published in Nature in June 2024 titled, “A disease-associated gene desert directs macrophage inflammation through ETS2”. Here, Stankey et al. use a cutting-edge functional genomic strategy to identify a novel therapeutic target for the treatment of inflammatory bowel disease. Paper: https://pubmed.ncbi.nlm.nih.gov/38839969/ To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or X (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Fri, May 24, 2024
#20: Cancer, Metabolism, T cells, and Spatial Transcriptomics with Dr. Miguel Reina-Campos, Ph.D.
Dr. Miguel Reina-Campos is an Assistant Professor at the La Jolla Institute for Immunology in La Jolla, California. The Reina lab seeks to understand the underlying principles governing tissue immune networks that enable robust and long-term protection against infection and tumors. In this conversation, Miguel and Kellen talk about cancer, metabolism, tissue resident memory T cells, spatial transcriptomics, advice for postdocs pursuing academia, and much more. Reina Lab: https://www.lji.org/labs/reina-lab/ Reina BioRxiv 2024: https://pubmed.ncbi.nlm.nih.gov/38585842/ Reina Nature 2023: https://pubmed.ncbi.nlm.nih.gov/37648857/ Reina Cancer Cell 2019: https://pubmed.ncbi.nlm.nih.gov/30827887/ Reina Nature Reviews Immunology 2021: https://pubmed.ncbi.nlm.nih.gov/33981085/ Twitter/X: @MReinaCampos To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or X (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Mon, May 15, 2023
#19: Lymphatics, stem cells, and postdocs with Dr. Shiri Gur-Cohen, Ph.D.
Dr. Gur-Cohen is an Assistant Professor of Medicine in the Division of Regenerative Medicine at the University of California, San Diego. Dr. Gur-Cohen’s work has unearthed the lymphatic capillary network as a novel stem cell niche component, and her multidisciplinary strategy has advanced our knowledge of how stem cells synchronize and coordinate tissue regeneration. In this conversation, Shiri and Kellen talk about stem cells, lymphatics, and microscopy. As a relatively new principal investigator, Shiri has a lot of advice for trainees in regards to choosing a postdoc, and she talks with Kellen about the topic at length in this conversation. Gur-Cohen lab website: https://gurcohenlab.com/ Lymphatics stem cell interaction paper: https://pubmed.ncbi.nlm.nih.gov/31672914/ To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Fri, March 24, 2023
#18: Unconventional T cells with Dr. Mitchell Kronenberg, Ph.D.
In this episode, Kellen speaks with Dr. Mitchell Kronenberg. Mitch is the chief scientific officer of the La Jolla Institute for Immunology, an adjunct professor at UC San Diego, and the co-director of a collaborative effort between the La Jolla Institute and UC San Diego called the Program in Immunology. Mitch and Kellen talk about unconventional T cells, autoimmunity, barrier immunity, chimeric antigen receptor (CAR) T cells, and the future of immunology. They also discuss Mitch’s philosophies related to science, mentorship, and life. Recent Kronenberg lab paper with intravital microscopy: https://pubmed.ncbi.nlm.nih.gov/35905286/ Kronenberg lab website: https://www.lji.org/labs/kronenberg/ Mitch’s Wikipedia page: https://en.wikipedia.org/wiki/Mitchell_Kronenberg Correction: When Kellen mentioned the published CAR T trial in human autoimmunity, he misspoke and said multiple sclerosis (MS) but the trial he was referring to was in patients with lupus. That said, published preclinical data suggests CAR T therapy may also work in MS patients. CAR T cell therapy in patients with lupus: https://pubmed.ncbi.nlm.nih.gov/36109639/ CAR T cell therapy in MS mouse model: https://pubmed.ncbi.nlm.nih.gov/36206355/ Thank you to our sponsors, NCI & CCMI! To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Fri, January 27, 2023
#17: Gut microbiome therapeutics with Dr. Amir Zarrinpar, M.D. Ph.D.
In this episode, Kellen speaks with Dr. Amir Zarrinpar. Amir is a board-certified gastroenterologist and an assistant professor at UC San Diego in the department of medicine. He completed his undergrad at Harvard, M.D. and Ph.D. at UCSD, and postdoc at the Salk Institute in Satchin Panda’s lab. In this conversation, Amir and Kellen talk about diabetes and obesity, time-restricted feeding, and engineered native bacteria—highlighting the Zarrinpar lab’s recent paper published in the journal Cell. Kellen and Amir also dig into Amir’s philosophies related to science, mentorship, and life. Live bacterial therapeutics paper: https://pubmed.ncbi.nlm.nih.gov/35931082/ Zarrinpar Lab website: https://zarrinparlab.org/ Thank you to our sponsors, NCI & CCMI! To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Thu, November 10, 2022
#16: Inflammatory bowel disease and proteomics with Dr. David Gonzalez, Ph.D.
In this episode, Kellen speaks with Dr. David Gonzalez. David is an associate professor at UC San Diego in the pharmacology department of the school of medicine and the Skaggs school of pharmacy. He’s also the founder and director of the UCSD collaborative center for multiplexed proteomics. The Gonzalez lab researches host-microbe interactions and specializes in proteomics approaches. Kellen and David talk about David’s inspirational journey to becoming a principal investigator. They also discuss proteomics, mentorship, and two of the Gonzalez lab’s recent publications related to inflammatory bowel disease (linked below). IBD proteomics papers: https://pubmed.ncbi.nlm.nih.gov/35999575/ https://pubmed.ncbi.nlm.nih.gov/35087228/ Gonzalez lab website: https://www.gonzalezlab.org/ Thank you to our sponsors, NCI & CCMI. Please take a few minutes to write us a review wherever you listened to this podcast—it will help us communicate great science. Finally, we would love to hear from you. Please send any questions or comments to @KellenCavagnero on Twitter.
Sun, June 19, 2022
#15: Antimicrobial resistance with Dr. Victor Nizet, M.D.
In this episode, Kellen interviews Dr. Victor Nizet, a distinguished professor of pediatrics and pharmaceutical sciences at UCSD and the vice chair of basic research in the department of pediatrics at UCSD. Kellen and Victor discuss one of the Nizet lab’s recent publications (led by Josh Sun, Pharm.D. Ph.D.) identifying novel treatment strategies for Staph aureus-induced sepsis. Kellen and Victor also talk about Victor’s career path and scientific philosophies. S. aureus-induced sepsis paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121309/ Nizet lab website: http://nizetlab.ucsd.edu/ Victor’s Twitter handle: @victornizet Thank you to our sponsors, NCI & CCMI! To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Sat, April 09, 2022
#14: Fibrosis in CNS autoimmunity with Dr. Richard Daneman, Ph.D.
In this episode, Kellen sits down for a conversation with Richard Daneman, an associate professor of neurosciences and pharmacology at UCSD. Kellen and Rich discuss the Daneman lab’s recent paper identifying a novel role of fibroblasts in the central nervous system as well as Rich’s philosophies about science and mentorship. CNS fibroblast paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877789/ Daneman website: https://www.danemanlab.com/ Thank you to our sponsors, NCI & CCMI! To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Sat, February 19, 2022
#13: Immune fibroblastic cells with Dr. Richard Gallo, M.D. Ph.D.
In this episode, Kellen is joined by his thesis advisor Dr. Richard Gallo, a Distinguished Professor and the Founding Chairman of the Department of Dermatology at the University of California, San Diego. Kellen and Rich discuss two recent publications from the Gallo lab related to the host defense process “reactive adipogenesis” and also talk about Rich’s background, advice for trainees, and more. Acne paper: https://pubmed.ncbi.nlm.nih.gov/35171653/ Skin-gut paper: https://pubmed.ncbi.nlm.nih.gov/34720087/ Thank you to our sponsors, NCI & CCMI. Please take a few minutes to write us a review wherever you listened to this podcast—it will help us spread science! As always, please send any questions or comments to @KellenCavagnero on Twitter.
Wed, December 29, 2021
#12: Omental fat, the “policeman of the abdomen”
Omental adipose tissue has been considered an important component of host defense since at least 1906 when it was deemed “the policeman of the abdomen”. The precise mechanisms underlying omental host defense, however, remain elusive. Here, Kellen discusses a recent publication investigating how omental host defense works. The report titled “Stromal cells covering omental fat-associated lymphoid clusters trigger formation of neutrophil aggregates to capture peritoneal contaminants” was written by Lucy Helen Jackson-Jones et al. and published in Immunity April 2020. Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156918/ Commentary: https://pubmed.ncbi.nlm.nih.gov/32294403/ Thank you to our new sponsors, NCI & CCMI! To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Fri, November 26, 2021
#11: Microbiome therapeutics with Dr. Alan O’Neill, Ph.D.
This is a special episode of Inflammatory Content as it is our first episode with a guest! Dr. Alan O’Neill, Ph.D. joins Kellen to discuss his work on microbiome therapeutics—highlighting his recent report in eLife (link below)—as well as his overall scientific journey. Dr. O’Neill’s recent publication (open access): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592530/ Dr. O’Neill graciously offered to provide his personal email (aloneill@health.ucsd.edu) to anyone wanting to get in contact with him. To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Mon, June 28, 2021
#10: Cuts, commensals, and chemokines
Getting physically injured is no fun—it can often take long periods of time to recover. What if we could accelerate the wound healing process? Here, Kellen dissects an original article, titled “The commensal skin microbiota triggers type I IFN-dependent innate repair responses in injured skin”, that reveals mechanisms underlying skin injury and identifies novel therapeutic approaches to speed up healing. The report was written by Jeremy Di Domizio et al. and was published in Nature Immunology in July of 2020. Paper: https://www.nature.com/articles/s41590-020-0721-6 Commentary: https://www.nature.com/articles/s41590-020-0755-9?proof=t To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Sat, July 18, 2020
#9: ILC2s and cancer
Cutting-edge approaches to combat tumor development involve transplantation of anti-tumor T cells and natural killer cells. Natural killer (NK) cells belong to a greater family of innate lymphoid cells which includes the more recently described group 1, 2, and 3 innate lymphoid cells (ILCs). Unlike NK and T cells, the role of non-NK ILCs in tumor immunity remains unclear. In this episode, Kellen highlights a 2020 report in Nature describing the role of ILC2s in pancreatic cancer. The article was written by John Alec Moral and colleagues and is titled “ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity”. Paper: https://www.nature.com/articles/s41586-020-2015-4 Review: https://pubmed.ncbi.nlm.nih.gov/30209347/ To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Mon, May 25, 2020
#8: Epigenome editing
Fragile X syndrome is a genetic disorder and the leading cause of intellectual disability and autism. There is no treatment. In this episode, Kellen discusses recent gene therapy advances for treating Fragile X syndrome. The article highlighted in this episode was written by X. Shawn Liu and colleagues from Rudolf Jaenisch’s lab at the Whitehead Institute and is titled “Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene”. Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375087/ To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Thu, March 26, 2020
#7: COVID19 PSA and unconventional T cells
Medical systems around the world need our help with COVID19. After sharing an important PSA, Kellen dives into the topic of unconventional T cells. These novel immune subsets have unique functions with great therapeutic potential. In this episode, a seminal paper by Michael Crowther and colleagues is discussed. It’s titled, “Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1”. Paper: https://www.ncbi.nlm.nih.gov/pubmed/31959982 Review: https://www.ncbi.nlm.nih.gov/pubmed/30397170 To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Sat, March 21, 2020
#6: Biofilm architecture
Antibiotic resistance is an enormous public health problem. The prevalence of superbugs is increasing over time, whereas the number of drugs available to treat these microbes is not. Bacterial communities called biofilms harbor strains of bacteria that persist in the face of antibiotic therapy. Thus, in order to tackle the problem of antibiotic resistance, we must better understand biofilms. In this episode, Kellen covers a recent report on this topic by Fransisco Diaz-Pascual and colleagues titled, “Breakdown of Vibrio cholerae biofilm architecture induced by antibiotics disrupts community barrier function”. Paper: https://www.ncbi.nlm.nih.gov/pubmed/31659297 Review: https://www.ncbi.nlm.nih.gov/pubmed/31295420 To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Sat, February 29, 2020
#5: Bacteria and immunotherapy
Engineering bacteria to kill cancer cells… Sounds like science fiction, right? Well, it’s actually all science, no fiction! Sreyan Chowdhury and colleagues from Tal Danino’s lab at Columbia University describe this novel therapeutic approach in their recent Nature Medicine publication, “Programmable bacteria induce durable tumor regression and systemic antitumor immunity”. Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688650/ Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558487/ Video: https://www.youtube.com/watch?v=fnpIIZrjMtM&t=18s To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Sun, February 02, 2020
#4: ILC2s and neutrophils
In this episode, Kellen covers a topic near and dear to his heart – group two innate lymphoid cells, or ILC2s. Specifically, Kellen discusses the original article titled “Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte–dendritic cell antigen presentation”, which was published in the journal Science Immunology in November 2019 by Dhiren Patel and colleagues. Paper: https://immunology.sciencemag.org/content/4/41/eaax7006/tab-pdf Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614509/ (shameless self-promo) To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Thu, January 02, 2020
#3: Commensal viruses
When most people think of viruses, they usually think of the negative aspect of viruses –- agents of infectious disease. We, however, are not most people! Not only are viruses useful biotechnological tools, but they are also capable of promoting health outcomes in disease models. In this episode, Kellen covers a report released in December 2019 in Nature Immunology by Lei Liu, Tao Gong, and colleagues titled “Commensal viruses maintain intestinal intraepithelial lymphocytes via noncanonical RIG-I signaling”. Paper: https://www.nature.com/articles/s41590-019-0513-z Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140792/ To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Wed, January 01, 2020
#2: Plant medicine
Plants are a great source of fiber and micronutrients, which makes them an important component of a heathy diet. However, it was recently shown that there is another aspect of plants that allows them to contribute to well-being –- exosomes. In this episode, Kellen reviews a paper published in 2018 in Cell Host & Microbe by Yun Teng and colleagues titled “Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota”. Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746408/ To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
Fri, December 27, 2019
#1: Introduction
Brief introduction of what this podcast will entail and the reason behind its creation. To help us spread science, please consider writing a review, sharing this episode with your friends and colleagues, or donating to support our work (Venmo @Kellen-Cavagnero). Please reach out to us via email (kcavagnero@gmail.com) or Twitter (@KellenCavagnero) with any questions, comments, topic suggestions, etc.
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